Publication: Loss of Metabolic Oscillations in a Multicellular Computational Islet of the Pancreas
Introduction
Applications
Tools
Research Groups
Workshops
Publications
   List Publications
   Advanced Search
   Info
   Add Publications
My Account
About

Loss of Metabolic Oscillations in a Multicellular Computational Islet of the Pancreas

- Article in a journal -
 

Area
Biomedicine

Author(s)
Jane Pan , Gemma Gearhart , Shuai Jiang , Thomas J. May

Published in
UMBC Review

Year
2014

Abstract
As my freshman year was coming to a close, my anxiety was gradually increasing because my plans for the summer were still unknown. Little did I know, I was only one e-mail away from spending eight weeks of my summer working in the Research Experience for Undergrauates (REU) site: Interdisciplinary Program in High Performance Computing hosted in the Department of Mathematics and Statistics at UMBC. Ever since I received an e-mail confirming my eligibility to participate in the program from my program directors Dr. Matthias Gobbert and Dr. Nagaraj Neerchal, I was not only exposed to a new learning environment, but I was also introduced to respected faculty members on campus as well as participants from across the country. My team’s research during the eight weeks of the summer program involved examining the patterns that are exhibited by pancreatic beta-cells, which are the biological units responsible for secreting insulin into the bloodstream. Through modifying and implementing existing code in the mathematical software package MATLAB, we were able to simulate the cells’ behaviors by manipulating various parameters. Understanding the factors that affect insulin secretion and finding conditions that cause beta-cells to behave in certain ways will allow researchers to gain a clearer insight into potential treatments for diabetes.

AD Tools
ADiMat

BibTeX
@ARTICLE{
         Pan2014LoM,
       author = "Jane Pan and Gemma Gearhart and Shuai Jiang and Thomas J. May",
       title = "Loss of Metabolic Oscillations in a Multicellular Computational Islet of the
         Pancreas",
       journal = "UMBC Review",
       year = "2014",
       volume = "15",
       pages = "31--53",
       abstract = "As my freshman year was coming to a close, my anxiety was gradually increasing
         because my plans for the summer were still unknown. Little did I know, I was only one e-mail away
         from spending eight weeks of my summer working in the Research Experience for Undergrauates (REU)
         site: Interdisciplinary Program in High Performance Computing hosted in the Department of
         Mathematics and Statistics at UMBC. Ever since I received an e-mail confirming my eligibility to
         participate in the program from my program directors Dr. Matthias Gobbert and Dr. Nagaraj Neerchal,
         I was not only exposed to a new learning environment, but I was also introduced to respected faculty
         members on campus as well as participants from across the country. My team’s research
         during the eight weeks of the summer program involved examining the patterns that are exhibited by
         pancreatic beta-cells, which are the biological units responsible for secreting insulin into the
         bloodstream. Through modifying and implementing existing code in the mathematical software package
         MATLAB, we were able to simulate the cells’ behaviors by manipulating various parameters.
         Understanding the factors that affect insulin secretion and finding conditions that cause beta-cells
         to behave in certain ways will allow researchers to gain a clearer insight into potential treatments
         for diabetes.",
       ad_area = "Biomedicine",
       ad_tools = "ADiMat"
}


back
  

Contact:
autodiff.org
Username:
Password:
(lost password)